An inflammatory response is a component of the immune response in the human body. The reaction is typically triggered by internal and external factors, but the common trigger is when microorganisms venture into sites where they do not belong. In the inflammation process, the body’s immune system usually recognizes damaged cells, pathogens, and irritants as it embarks on the healing process.In response to pathogens, harmful microbes, and dangerous chemical reactions, the normal biological response from the body is that it will attempt to remove the pathogenic microbes. After the inflammatory response process is initiated, it often proceeds following a certain course of events up to the point where the source of inflammation is annihilated. Typically, the body would not have the ability to heal wounds, infections, or tissue damage without the occurrence of an inflammatory response.
In some cases, inflammation arises when the immune system fights against its own cells by mistake thus causing harmful responses. For example, there are conditions that cause inflammatory effects such as psoriasis, rheumatoid arthritis, or Crohn’s disease. The main symptoms of inflammation include immobility, pain, redness, heat, or swelling. Pain is usually caused by chemicals that stimulate nerve endings, and subsequently, cause a sensitive feeling in the area. Additionally, swelling is a factor caused by the accumulation of fluid. With the influx of blood to the affected area of the body, the blood causes a characteristic redness and produces heat.During inflammatory responses, immune cells release different compounds known as the inflammatory mediators. The inflammatory mediators typically include tissue hormones such as histamine or bradykinin. Such compounds cause expansion of the blood vessels in the tissue and allow blood to reach the affected tissue. Inflammatory mediators also lead to an increase in permeability of the narrow vessels to allow more defense cells to enter the affected area. In the event that the inflammation worsens, then the result is sepsis. Sepsis arises when bacteria in the affected area multiply rapidly and increase in the bloodstream in large quantities. There are various causes of inflammation and this article delves into some of the common causes.
In some cases, inflammation arises when the immune system fights against its own cells by mistake thus causing harmful responses. For example, there are conditions that cause inflammatory effects such as psoriasis, rheumatoid arthritis, or Crohn’s disease. The main symptoms of inflammation include immobility, pain, redness, heat, or swelling. Pain is usually caused by chemicals that stimulate nerve endings, and subsequently, cause a sensitive feeling in the area. Additionally, swelling is a factor caused by the accumulation of fluid. With the influx of blood to the affected area of the body, the blood causes a characteristic redness and produces heat.During inflammatory responses, immune cells release different compounds known as the inflammatory mediators. The inflammatory mediators typically include tissue hormones such as histamine or bradykinin. Such compounds cause expansion of the blood vessels in the tissue and allow blood to reach the affected tissue. Inflammatory mediators also lead to an increase in permeability of the narrow vessels to allow more defense cells to enter the affected area. In the event that the inflammation worsens, then the result is sepsis. Sepsis arises when bacteria in the affected area multiply rapidly and increase in the bloodstream in large quantities. There are various causes of inflammation and this article delves into some of the common causes.